The following articles (labelled with PubMed ID or TBD) are for your review| PMID | Article Title | Published | Deposition |
|---|
| 36383928 |
Engineering the Cyclization Loop of MCoTI-II Generates Targeted Cyclotides that Potently Inhibit Factor XIIa. |
08-DEC-2022 |
20-APR-2024 |
| 31810785 |
Tyrosinase inhibitors as potential antibacterial agents. |
01-FEB-2020 |
19-APR-2024 |
| 35640100 |
Glenthmycins A-M: Macrocyclic Spirotetronate Polyketide Antibacterials from the Australian Pasture Plant-Derived |
24-JUN-2022 |
23-JUN-2023 |
| 35073486 |
Glenthenamines A-F: Enamine Pyranonaphthoquinones from the Australian Pasture Plant Derived |
25-FEB-2022 |
22-JUN-2023 |
| 34671739 |
Posttranslational modifications of ?-conotoxins: sulfotyrosine and C-terminal amidation stabilise structures and increase acetylcholine receptor binding. |
23-SEP-2021 |
22-JUN-2023 |
| 35984914 |
Modifying a Hydroxyl Patch in Glucagon-like Peptide 1 Produces Biased Agonists with Unique Signaling Profiles. |
08-SEP-2022 |
21-JUN-2023 |
| 36167503 |
Late-Stage Functionalization with Cysteine Staples Generates Potent and Selective Melanocortin Receptor-1 Agonists. |
13-OCT-2022 |
19-JUN-2023 |
| 36439982 |
Synthesis of full-length homodimer ?D-VxXXB that targets human ?7 nicotinic acetylcholine receptors. |
16-NOV-2022 |
19-JUN-2023 |
| 35308021 |
Inhibition of N-type calcium ion channels by tricyclic antidepressants - experimental and theoretical justification for their use for neuropathic pain. |
23-FEB-2022 |
18-JUN-2023 |
| 34762432 |
Development of Potent and Selective Agonists for Complement C5a Receptor 1 with In Vivo Activity. |
25-NOV-2021 |
07-MAR-2023 |
| 35067062 |
Neochrysosporazines: Precursor-Directed Biosynthesis Defines a Marine-Derived Fungal Natural Product P-Glycoprotein Inhibitory Pharmacophore. |
10-FEB-2022 |
06-MAR-2023 |
| 33356222 |
Bioactive Cyclization Optimizes the Affinity of a Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Peptide Inhibitor. |
11-MAR-2021 |
05-MAR-2023 |
| 34197114 |
Melanocortin 1 Receptor Agonists Based on a Bivalent, Bicyclic Peptide Framework. |
22-JUL-2021 |
05-MAR-2023 |
| 33891818 |
Xanthine-Guanine-Hypoxanthine Phosphoribosyltransferase-A Putative Target for Drug Discovery against Gastrointestinal Tract Infections. |
13-MAY-2021 |
22-AUG-2022 |
| 33570940 |
HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates. |
25-FEB-2021 |
29-MAR-2022 |
| 32828422 |
The neuronal calcium ion channel activity of constrained analogues of MONIRO-1. |
15-SEP-2020 |
28-MAR-2022 |
| 26824523 |
Engineering of a Novel Simplified Human Insulin-Like Peptide 5 Agonist. |
10-MAR-2016 |
27-MAR-2022 |
| 29584430 |
Bicyclic Helical Peptides as Dual Inhibitors Selective for Bcl2A1 and Mcl-1 Proteins. |
12-APR-2018 |
27-MAR-2022 |
| 29378414 |
The E15R Point Mutation in Scorpion Toxin Cn2 Uncouples Its Depressant and Excitatory Activities on Human Na |
22-FEB-2018 |
27-MAR-2022 |
| 33039562 |
Rapid discovery of a selective butyrylcholinesterase inhibitor using structure-based virtual screening. |
15-DEC-2020 |
25-MAR-2022 |
| 32383881 |
Achiral Derivatives of Hydroxamate AR-42 Potently Inhibit Class I HDAC Enzymes and Cancer Cell Proliferation. |
11-JUN-2020 |
11-AUG-2021 |
| 31975579 |
Chrysosporazines F-M: P-Glycoprotein Inhibitory Phenylpropanoid Piperazines from an Australian Marine Fish Derived Fungus, |
28-FEB-2020 |
11-AUG-2021 |
| 27405689 |
Discovery and Structure-Activity Relationships of a Highly Selective Butyrylcholinesterase Inhibitor by Structure-Based Virtual Screening. |
25-AUG-2016 |
28-FEB-2021 |
| 27434175 |
Substrate-Guided Design of Selective FXIIa Inhibitors Based on the Plant-Derived Momordica cochinchinensis Trypsin Inhibitor-II (MCoTI-II) Scaffold. |
11-AUG-2016 |
27-FEB-2021 |
| 31855419 |
Binding Loop Substitutions in the Cyclic Peptide SFTI-1 Generate Potent and Selective Chymase Inhibitors. |
23-JAN-2020 |
23-FEB-2021 |
| 30520638 |
Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma. |
24-JAN-2019 |
22-FEB-2021 |
| 31445230 |
Synthesis, evaluation and structural investigations of potent purple acid phosphatase inhibitors as drug leads for osteoporosis. |
15-NOV-2019 |
21-FEB-2021 |
| 30888159 |
Amino Acid Scanning at P5' within the Bowman-Birk Inhibitory Loop Reveals Specificity Trends for Diverse Serine Proteases. |
11-APR-2019 |
21-FEB-2021 |
| 31625738 |
Trivirensols: Selectively Bacteriostatic Sesquiterpene Trimers from the Australian Termite Nest-Derived Fungus |
22-NOV-2019 |
19-FEB-2021 |
| 30613336 |
Potent, Selective, and Cell-Penetrating Inhibitors of Kallikrein-Related Peptidase 4 Based on the Cyclic Peptide MCoTI-II. |
13-DEC-2018 |
19-FEB-2021 |
| 31413811 |
Iterative Optimization of the Cyclic Peptide SFTI-1 Yields Potent Inhibitors of Neutrophil Proteinase 3. |
08-AUG-2019 |
17-FEB-2021 |
| 26522948 |
Potent complement C3a receptor agonists derived from oxazole amino acids: Structure-activity relationships. |
01-DEC-2015 |
04-SEP-2020 |
| 23566299 |
Determination of the ?-conotoxin Vc1.1 binding site on the ?9?10 nicotinic acetylcholine receptor. |
09-MAY-2013 |
31-AUG-2020 |
| 22115595 |
3-mercapto-1,2,4-triazoles and N-acylated thiosemicarbazides as metallo-?-lactamase inhibitors. |
01-JAN-2012 |
29-AUG-2020 |
| 30107365 |
Purple acid phosphatase inhibitors as leads for osteoporosis chemotherapeutics. |
05-SEP-2018 |
18-AUG-2020 |
| 30265958 |
Pyrrolidine nucleoside bisphosphonates as antituberculosis agents targeting hypoxanthine-guanine phosphoribosyltransferase. |
05-NOV-2018 |
18-AUG-2020 |
| 30322754 |
Antifungal benzo[b]thiophene 1,1-dioxide IMPDH inhibitors exhibit pan-assay interference (PAINS) profiles. |
01-NOV-2018 |
18-AUG-2020 |
| 28977749 |
Chemical Approaches to Modulating Complement-Mediated Diseases. |
26-APR-2018 |
17-AUG-2020 |
| 29936356 |
Engineering potent mesotrypsin inhibitors based on the plant-derived cyclic peptide, sunflower trypsin inhibitor-1. |
15-JUL-2018 |
15-AUG-2020 |
| 29338910 |
Synthesis of deuterium-labelled analogues of NLRP3 inflammasome inhibitor MCC950. |
15-FEB-2018 |
15-AUG-2020 |
| 28614759 |
Structure-activity relationship study and optimisation of 2-aminopyrrole-1-benzyl-4,5-diphenyl-1H-pyrrole-3-carbonitrile as a broad spectrum metallo-?-lactamase inhibitor. |
08-SEP-2017 |
21-APR-2020 |
| 28045523 |
Design of Potent and Selective Cathepsin G Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold. |
26-JAN-2017 |
23-FEB-2020 |
| 29605997 |
Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1. |
26-APR-2018 |
01-FEB-2020 |
| 26819675 |
Potent Small Agonists of Protease Activated Receptor 2. |
14-JAN-2016 |
06-JUN-2019 |
| 27823886 |
Helixconstraints and amino acid substitution in GLP-1 increase cAMP and insulin secretion but not beta-arrestin 2 signaling. |
15-FEB-2017 |
07-MAY-2019 |
| 28105269 |
Electrophilic Helical Peptides That Bond Covalently, Irreversibly, and Selectively in a Protein-Protein Interaction Site. |
12-JAN-2017 |
07-SEP-2018 |
| 27856238 |
Evaluation of known and novel inhibitors of Orai1-mediated store operated Ca |
01-JAN-2017 |
15-AUG-2018 |
| 27994760 |
PAR2 Modulators Derived from GB88. |
08-DEC-2016 |
07-AUG-2018 |
| 27994733 |
Identification, Synthesis, and Biological Evaluation of the Major Human Metabolite of NLRP3 Inflammasome Inhibitor MCC950. |
08-DEC-2016 |
25-JUL-2018 |
| 28376304 |
Origins of PDZ Binding Specificity. A Computational and Experimental Study Using NHERF1 and the Parathyroid Hormone Receptor. |
23-MAY-2017 |
30-MAY-2017 |
| 26725028 |
Benzylamide antagonists of protease activated receptor 2 with anti-inflammatory activity. |
25-JAN-2016 |
30-MAY-2017 |
| 28163017 |
Small-Molecule Inhibitors of the SOX18 Transcription Factor. |
16-MAR-2017 |
27-APR-2017 |
| 26352676 |
Cyclic alpha-conotoxin peptidomimetic chimeras as potent GLP-1R agonists. |
09-OCT-2015 |
17-DEC-2016 |
| 25915781 |
First Crystal Structures of Mycobacterium tuberculosis 6-Oxopurine Phosphoribosyltransferase: Complexes with GMP and Pyrophosphate and with Acyclic Nucleoside Phosphonates Whose Prodrugs Have Antituberculosis Activity. |
11-JUN-2015 |
09-OCT-2016 |
| US9200020 |
6-oxopurine phosphoribosyltransferase inhibitors |
01-DEC-2015 |
27-SEP-2016 |
| US9199976 |
Haematopoietic-prostaglandin D2 synthase inhibitors |
01-DEC-2015 |
27-SEP-2016 |
| 25494538 |
Aza-acyclic nucleoside phosphonates containing a second phosphonate group as inhibitors of the human, Plasmodium falciparum and vivax 6-oxopurine phosphoribosyltransferases and their prodrugs as antimalarial agents. |
22-JAN-2015 |
03-APR-2016 |
| 25259874 |
Potent heterocyclic ligands for human complement c3a receptor. |
23-OCT-2014 |
09-MAR-2016 |
| 24583353 |
The applications of binuclear metallohydrolases in medicine: recent advances in the design and development of novel drug leads for purple acid phosphatases, metallo-ß-lactamases and arginases. |
21-MAR-2014 |
07-FEB-2015 |
| 23895492 |
Toward drugs for protease-activated receptor 2 (PAR2). |
10-OCT-2013 |
13-APR-2014 |
| 23685178 |
Australian marine sponge alkaloids as a new class of glycine-gated chloride channel receptor modulator. |
14-JUN-2013 |
13-APR-2014 |
| 23237384 |
Sulfonylureas have antifungal activity and are potent inhibitors of Candida albicans acetohydroxyacid synthase. |
10-JAN-2013 |
24-SEP-2013 |
| 23448281 |
Acyclic nucleoside phosphonates containing a second phosphonate group are potent inhibitors of 6-oxopurine phosphoribosyltransferases and have antimalarial activity. |
28-MAR-2013 |
24-SEP-2013 |
| 22929233 |
A focused sulfated glycoconjugate Ugi library for probing heparan sulfate-binding angiogenic growth factors. |
17-SEP-2012 |
22-MAY-2013 |
| 23022277 |
Synthesis, biological activity and structure-activity relationship of endomorphin-1/substance P derivatives. |
15-OCT-2012 |
17-MAY-2013 |
| 22680612 |
Synthesis and biological evaluation of an orally active glycosylated endomorphin-1. |
28-JUN-2012 |
17-MAY-2013 |
| 17428804 |
chi-Conotoxin and tricyclic antidepressant interactions at the norepinephrine transporter define a new transporter model. |
11-JUN-2007 |
16-DEC-2012 |
| 15027855 |
Countering cooperative effects in protease inhibitors using constrained beta-strand-mimicking templates in focused combinatorial libraries. |
18-MAR-2004 |
30-NOV-2012 |
| 11000004 |
Synthesis, stability, antiviral activity, and protease-bound structures of substrate-mimicking constrained macrocyclic inhibitors of HIV-1 protease. |
12-OCT-2000 |
15-NOV-2012 |
| 10411589 |
Comparison of the pharmacological properties of cloned rat, human, and bovine norepinephrine transporters. |
XX-XXX-1999 |
12-APR-2012 |
| 21459576 |
Synthesis, modelling and kinetic assays of potent inhibitors of purple acid phosphatase. |
02-MAY-2011 |
04-DEC-2011 |
| 21117646 |
Modulating oxytocin activity and plasma stability by disulfide bond engineering. |
17-DEC-2010 |
20-AUG-2011 |
| 20951583 |
Antimalarial histone deacetylase inhibitors containing cinnamate or NSAID components. |
08-NOV-2010 |
14-JUN-2011 |
| 20947351 |
Inhibitors selective for HDAC6 in enzymes and cells. |
08-NOV-2010 |
14-JUN-2011 |
| 18268084 |
DNA gyrase from the albicidin producer Xanthomonas albilineans has multiple-antibiotic-resistance and unusual enzymatic properties. |
27-MAR-2008 |
13-JUN-2011 |
| 20873792 |
Novel agonists and antagonists for human protease activated receptor 2. |
21-OCT-2010 |
13-JUN-2011 |
| 20684598 |
Development and characterization of new inhibitors of the human and mouse hematopoietic prostaglandin D(2) synthases. |
05-AUG-2010 |
20-MAR-2011 |
| 20527893 |
Selective hexapeptide agonists and antagonists for human complement C3a receptor. |
01-JUL-2010 |
21-NOV-2010 |
| 20346682 |
Ircinialactams: subunit-selective glycine receptor modulators from Australian sponges of the family Irciniidae. |
12-APR-2010 |
19-NOV-2010 |
| 19743866 |
Structure-activity relationships for substrate-based inhibitors of human complement factor B. |
01-OCT-2009 |
18-NOV-2010 |
| 20170165 |
Noncovalent tripeptidyl benzyl- and cyclohexyl-amine inhibitors of the cysteine protease caspase-1. |
18-MAR-2010 |
02-SEP-2010 |
| 19683451 |
Omega-conotoxin GVIA mimetics based on an anthranilamide core: effect of variation in ammonium side chain lengths and incorporation of fluorine. |
02-SEP-2009 |
31-AUG-2010 |
| 19939518 |
Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D2 synthase. |
01-FEB-2010 |
29-AUG-2010 |
| 19527031 |
Inhibition of hypoxanthine-guanine phosphoribosyltransferase by acyclic nucleoside phosphonates: a new class of antimalarial therapeutics. |
16-JUL-2009 |
26-AUG-2010 |
| 19010677 |
Inhibition of purple acid phosphatase with alpha-alkoxynaphthylmethylphosphonic acids. |
26-DEC-2008 |
11-JAN-2010 |
| 14971903 |
Chemical and functional identification and characterization of novel sulfated alpha-conotoxins from the cone snail Conus anemone. |
19-FEB-2004 |
10-NOV-2009 |
Search and Browse
